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This cascade precipitates tumor immune evasion through multifaceted mechanisms: functional impairment of effector immune cells, amplified secretion of immunosuppressive cytokines, upregulation of immune checkpoint molecules, and altered tumor-associated antigen presentation ( e.g

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"A lot of times, people have worked hard in therapy to be able to put those thoughts onto the back burner so they can be active and productive, and these thoughts arent impacting their daily functioning, says Smith